Oxidative stress and alopecia areata
نویسندگان
چکیده
Alopecia areata (AA) is an inflammatory and autoimmune disease presenting with non-scarring hair loss. The aethiopathogenesis of alopecia areata is unclear and many factors including autoimmunity, genetic predisposition, emotional and environmental stress are thought to play important roles in its development. Antioxidant/ oxidant balance perturbation is a common feature in autoimmune, emotional and environmental stress. Therefore, our paper discusses the implications of oxidative stress in alopecia areata.
منابع مشابه
Frequency of Stress, Anxiety and Depression in Patients with Alopecia Areata and Control Group Referring to Skin Clinics of Yazd City in 2017
Introduction: Alopecia areata is a fairly common disease characterized by patchy aria of hair loss. The role of psychological factors in the occurrence of alopecia areata has long been discussed. The present study was conducted to determine the frequency of stress and anxiety and depression in the patients with alopecia areata in Yazd City in 2017. Methods: This study was a cross-sectional stu...
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BACKGROUND Alopecia areata (AA) is an autoimmune, T-cell mediated, and chronic inflammatory disorder. The pathological mechanisms of disease are unclear, but oxidative stress may be involved. To our knowledge, no studies have examined the oxidative stress levels or biomarkers within the lesional area and skin surface in patients with AA. Similarly, adenosine deaminase (ADA) has not been charact...
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Background: Localized and extensive clinical subtypes of alopecia areata (AA) including alopecia totalis and alopecia universalis differ in genetic and immunologic aspects. Objective: Comparison of epidemiologic aspects of localized and extensive subtypes of AA. Patients and Methods: In a prospective descriptive study, 180 patients suffering from AA attending the skin clinics of Razi Hosp...
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The controversial role of psychosocial stress in alopecia areata has been discussed widely, but there has been little research into patients' subjective stress experiences and coping. The aim of this study was to explore general and specific coping strategies in alopecia areata and to assess the role of psychosocial stress in the onset and course of alopecia areata from the patient's viewpoint....
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Thirty cases of alopecia Areata from O.P.D. of Govt. Hospital, Madras were administered Indian Version of schedule of Recent Experience, Taylor's Manifest Anxiety Scale, Beck's Depressive Inventory, Hostility Direction and Hostility Questionnaire of Fould's and Cattell's 16 PF Questionnaire (Form E) to find out antecedent stress, anxiety, depression, hostility and personality factors. Thirty ca...
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